Design, synthesis and biological evaluation of a macrocyclic discodermolide/dictyostatin hybrid.
نویسندگان
چکیده
A 22-membered macrocyclic discodermolide/dictyostatin hybrid has been designed and synthesised; biological evaluation against a range of human cancer cell lines revealed significant levels of growth inhibition.
منابع مشابه
Total synthesis of a potent hybrid of the anticancer natural products dictyostatin and discodermolide.
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ورودعنوان ژورنال:
- Chemical communications
دوره 1 شماره
صفحات -
تاریخ انتشار 2007